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Step 1. Main paper Submission
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Step 2. Back up submission
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Submit with this checklist
Adapted from the
strobe guideline for observational studies (STROBES)
| S/N | Section | Question | answer |
| 1 | Title and abstract: | Study’s design in the title/abstract indicated | |
| 2 | Background/Rationale: | Informative/balanced summary of methods and key results provided in the abstract |
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| 3. | Objective: | Scientific background and rationale for reported investigation clearly explained |
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| 4. | Study design: | Key elements of the study design presented | |
| 5. | Setting: | The setting, locations, dates, periods of recruitment, exposure, follow-up, and data collection clearly described |
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| 6. | Participants: | Study type, Eligibility/matching criteria, participants selection, case ascertainment, control and follow up methods/source, number of exposed, unexposed, and controls per case |
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| 7. | Variables: | All outcomes, exposures, predictors, potential confounders, and effect modifiers; diagnostic criteria, clearly defined |
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| 8. | Data source/measurement: | Sources of data, methods of assessment (measurement); describe comparability of assessment method(s) given in detail |
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| 9 | Bias: | Efforts to address likely sources of bias defined | |
| 10. | Study size: | How the study size was derived clearly outlined | |
| 11. | Quantitative variables | How quantitative variables were analyzed include which groupings were chosen and why |
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| 12. | Statistical methods: | All statistical methods, including those used to control for confounding, examine subgroups and interactions, address missing data, loss to follow-up, matching of cases and controls, analyze sampling strategy and sensitivity explained | |
| 13 | Participants: | Numbers of individuals potentially, examined or confirmed eligible at each stage of the study and those included in the study or completing follow-up, and reasons for nonparticipation are clearly defined, Consider the use of a flow diagram | |
| 14. | Descriptive data: | Characteristics of study participants (e.g., demographic, clinical, social) and information on exposures and potential confounders, number of participants with missing data for each variable of interest, summarize follow-up time (e.g., average and total amount) clearly defined |
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| 15. | Outcome data: | Numbers of outcome events or summary measures over time, numbers in each exposure category, or summary measures of exposure and numbers of outcome events or summary measures, outlined |
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| 16. | Main results: | Have you given unadjusted estimates and, if applicable, confounder-adjusted estimates and their precision (e.g., 95% confidence interval); make clear which confounders were adjusted for and why they were included, report category boundaries when continuous variables were categorized. | |
| 17 | Other analysis: | Subgroups, interactions, and sensitivities reported | |
| 18. | Key results: | Key results in relation to study objectives reported | |
| 19 | Limitation: | limitations of the study, taking into account sources of potential bias or imprecision; discuss both direction and magnitude of any potential bias |
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| 20. | Interpretation: | Give a cautious overall interpretation of results considering objectives, limitations, the multiplicity of analyses, results from similar studies, and other relevant evidence | |
| 21 | Generalizability: | Discuss the generalizability (external validity) of the study results | |
| 22. | Funding: | the source of funding and the role of the funders for the present study and, if applicable, for the original study on which the present article is based Funding |
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